The ophthalmology market values innovation approaches, demonstrated by premiums paid for acquisition of first-in-class therapies and public market support of ophthalmology gene therapy companies.
Market Insight: Echoe Bouta, PhD, Scott Terchiak, and Oded Ben-Joseph, PhD, MBA
The ophthalmology market values innovative approaches, demonstrated by premiums paid for acquisition of first-in-class therapies and public market support of ophthalmology gene therapy companies.
Total economic burden of vision loss and eye disorders surpasses $130 billion in the U.S., a figure expected to rise due to the aging population. We examined recent ophthalmology market dynamics between 2015 and 2018, including industry-sponsored clinical trials, financing events, mergers and acquisition transactions and initial public offerings. These dynamics are utilized to assess the overall activity of the sector and interest by venture capitalists, strategic players and the public market.
This article examines the quiet but profound reset underway in U.S. biotech, triggered by a rare combination of forces: delayed or reduced federal funding, large pharma cutting mid-stage partnerships, and venture capital pulling back as exits evaporate. Based on insights from Dr. Stanislav Glezer, it reveals a market splitting in two — with capital chasing late-stage and very early assets while Phase 1–2 companies are stranded in the middle. The piece also exposes how government uncertainty, shrinking NIH support, and overlooked patient-behavior realities are forcing founders to rethink their entire company lifecycle. In today’s environment, survival requires new strategies, new geographies, and a deeper understanding of human factors that no protocol can fix.
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