When many people think of the National Capital region and the businesses that call it home, a handful of industries come to mind. Certainly the largest of which is government contracting.
Between the Pentagon and individual civilian agency headquarters, the Washington, D.C. region is home to a majority of the decision makers and influencers in the federal government. It’s for this reason that contractors with a wide range of specialties, from professional services and staffing, to homeland security and technology, call the area within and around the Capital Beltway home. In addition to these contracting companies are the financial services and banking companies, legal firms and other organizations that service that industry.
This article examines the quiet but profound reset underway in U.S. biotech, triggered by a rare combination of forces: delayed or reduced federal funding, large pharma cutting mid-stage partnerships, and venture capital pulling back as exits evaporate. Based on insights from Dr. Stanislav Glezer, it reveals a market splitting in two — with capital chasing late-stage and very early assets while Phase 1–2 companies are stranded in the middle. The piece also exposes how government uncertainty, shrinking NIH support, and overlooked patient-behavior realities are forcing founders to rethink their entire company lifecycle. In today’s environment, survival requires new strategies, new geographies, and a deeper understanding of human factors that no protocol can fix.
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